Thermoradiotherapy Using Ultrasound Hyperthermia System for Supraclavicular Lymph Node Metastasis.

概要

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Metastatic lymphnodes located in the subclavian region were treated with thermoradiotherapy using an ultrasound hyperthermia system. The mean size of tumor was 37mm diameters (range 30-55mm). Two cases were histologically diagnosed adenocarcinoma and one case was squamous cell carcinoma. The radiation dose was 40-64 Gy. The hyperthermia was performed once or twice a week, total number of session was 4 - 6. The ultrasound frequency of applicator was 1.0 MHz or 1.5 MHz. The temperature of tumor center was measured by thermo-couples. In three out of 4 cases the tumor temperature raised over 42.5 °C within about 6 minutes but temperature of skin surface were under 37.0 °C. Three cases had complete response and one case had partial response. Side effects were occurred in two cases, those were pain of clavicle and weakness of affected side arm and blister. The thermoradiotherapy using ultrasound hyperthermia system was considered to be useful modality for subclavian lymphnode metastasis.
日本ハイパーサーミア学会の論文