Clinical Usefulness of 1H-MRS for the Assessment of the Effects of Radiohyperthermochemotherapy in Bone and Soft Tissue Tumors.
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概要
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The <SUP>1</SUP>H-MR spectra of plasma obtained from two patients under treatment with radiohyperthermochemotherapy (RHC) for malignant bone and soft tissue tumors were studied and assessed for treatment efficacy. High lactate peaks were obtained, similar to those already reported in other malignant tumors. Changes in the area of lactate peaks reflected treatment effect in the two cases reported. The lactate peaks showed a time-dependent decline in case 1 in which RHC was successful. In contrast the lactate peaks did not show change in case 2, in which RHC was not effective. To our knowledge, this is the first report of its kind in the orthopedic field.<BR>There have been no useful serum markers for malignant tumors in the orthopedic field. The <SUP>1</SUP>H-MRS lactate peaks could contribute to assessment of treatment course in bone and soft tissue tumors.
- 日本ハイパーサーミア学会の論文
日本ハイパーサーミア学会 | 論文
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