A case report of acute bromovaleryl urea intoxication diagnosed by high density substance in the stomach on a CT scan

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A 48 year-old deep coma female was transfered to our emergency room by her commonlaw marriage husband by his car. Her pupils were miotic and reacted sluggish on a light stimulation. There were some bruises on her face and breast. Firstly, we suspected the cause of coma as a brain injury. But there were no abnormal findings in a head CT scan, nor chest, abdominal X-ray images. We unexpectedly observed high density substance in her stomach on a CT scan. This finding reminded us a radiopaque drug intoxication. Bromovaleryl urea is a wellknown radiopaque hypnotic drug. Later, four empty boxes of drug packages printed "WuttTM", which contains bromovareryl urea, were discovered in her house. After she became awake, she confirmed an overdose use of this drug and had a suicidal ideation. We found 4.5mg·dl-1 of bromine in her blood taken just after her admission. We diagnosed the cause of unconsciousness as acute bromovaleryl urea intoxication by a CT image which is more sensitive than a plain abdominal X-ray image in this case.
一般社団法人日本集中治療医学会の論文