The Effect of pH on the Growth of MRSA

概要

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The aim of this experiment was to determine the influence of pH on MRSA growth. MRSA growth wau suppressed in acidic medium, and the degree of suppression paralleled the degree of acidity. The results showed that MRSA hardly grew in the media with a pH below 4, few cultures were identified at pH 2 and 3. A bacteriocidal effect was noted in the media with a pH below 3. At pH 5, cultures were markedly inhibited, and even at pH 6, culture failed to yield certain strains of MRSA.The usefulness of antibiotics can not be denied, but proper implementation of infection control should be excuted to avoid the outbreaks of resistant pathogens. Although treatment with dilute hydrochloric acid (pH 2) may only be applicable in superficial infections such as MRSA colitis, it seems to be promising as an attempt of antimicrobial therapy without any induction of resistant strains.
一般社団法人日本集中治療医学会の論文