A Study of Autologous Transfusion with Erythropoietin.

概要

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Since March, 1994, 12 preoperatively deposited autologous transfusions with erythropoietin have been performed. Although the patients were of advanced age, we could obtain a sufficient volume of blood according to plan with the use of erythropoietin. All operations were completed, using only deposited autologous blood.No severe side effects were experienced. The increase of hemoglobin over a weekly period was -0.03g/dl (after blood was first obtained), +0.34g/dl (after obtaining blood for the second time), +0.96g/dl (after obtaining blood for the third time).The current guidelines for preoperatively deposited autologous transfusions state that it is to be desired that the hemoglobin level before obtaining blood is more than 11.0g/dl. However, in elderly people hemoglobin is often less than 11.0g/dl when blood is obtained. Five of our 12 cases did not satisfy the guidelines (>hemaglobin 11.0g/dl) in the course of blood deposition. It was attempted to obtain the planned 400ml of blood by carefully observing the patient's condition and were successful. It was concluded that hemoglobin levels continue to increase as time passes because of the effect of erythropoietin, therefore with the use of erythropoietin, obtaining the planned amount of autolognus blood from older patients, can be performed relatively safely even if hemoglobin is less than 11.0g/dl.
中国・四国整形外科学会の論文