Metastatic ability and expression of c-fos oncogene in cell clones of a spontaneous rat mammary tumor.
スポンサーリンク
概要
- 論文の詳細を見る
It was found that cell clones cl-2, cl-2r, cl-3, cl-4 and cl-6 of a spontaneous rat mammary tumor, c-SST-2, exhibit different degrees of metastatic ability: cl-2, cl-3, cl-6 were highly metastatic, while cl-2r and cl-4 were weakly metastatic. The expression of several oncogenes in these clones was examined. The amounts of myc mRNA in the clones were nearly the same. Expression of N-ras mRNA was higher in cl-2r and cl-4 than in cl-2, cl-3 and cl-6. On the other hand, the amounts of fos mRNA in the weakly metastatic clones were markedly lower than those in the highly metastatic clones. These results suggest that fos oncogene plays a role in the high metastatic ability of c-SST-2.
- 日本癌学会の論文
日本癌学会 | 論文
- Suppressive Effect of Prednisolone on Cytotoxicity of Lymphocytes from Normal Persons Against T24 Cells
- Organotropic Effect of N-Bis(2-hydroxypropyl)nitrosamine--Production of Lung and Liver Tumors by Its Oral Administration in Mice
- Effect of Dose on the Carcinogenic Activity of Orally Administered N-BIS(2-Hydroxypropyl)Nitrosamine in Rats
- Carcinogenic Activity of 3-Di(hydroxymethyl)amino-6-(5-nitro-2-furyletheny1)-1,2,4-triazine(panfuran-S)in Male Rats(Communication)
- Enhancement of pancreatic tumorigenesis of 4-hydroxyaminoquinoline 1-oxide by ethionine in rats (Note)