On the Distribution of Nucleic Acids in Tumor Cells of the MTK-Sarcoma Ⅲ
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概要
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By applications of the Feulgen reaction for DNA, the toluidine blue method for RNA and methyl green-pyronine technique for nucleic acids, the cytochemical relationship of the nucleolus and the nucleolus-associated chromatin was investigated in the tumor cells of the MTK-sarcoma III. From the results obtained it was suggested that; (1) In the rapidly growing tumor cells, the nucleolus occurs in very close connection with the nucleolus-associated chromatin, both cytochemically and morphologically. (2) The true nucleolus that is negative to the Feulgen reaction is probably surrounded by two somewhat different elements, highly polymerized DNA and depolymerized DNA. (3) The highly and depolymerized DNA, RNA and protein closely associated with one another to constitute the so-called nucleolus which appears as a large prominent and basophilic body in the nucleus.
- 北海道大學 = THE FACULTY OF SCIENCE, HOKKAIDO UNIVERSITYの論文
北海道大學 = THE FACULTY OF SCIENCE, HOKKAIDO UNIVERSITY | 論文
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