Effect of reactive oxygen species on cell adhesion: Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis.:Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in
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概要
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Adhesion of colon cancer cells (colo 201) and neutrophils to endothelial cells which had been briefly treated with hypoxanthine/xanthine oxidase, hydrogen peroxide, or peroxynitrite was analyzed in the absence of de novo protein synthesis using actinomycin D or cycloheximide. Hypoxanthine/xanthine oxidase treatments accelerated the adhesion of both colo 201 cells and neutrophils to endothelial cells, and these effects were blocked by SOD/catalase or EDTA. These data provided preliminary evidence for the fact that hydroxyl radicals directly affect the cell surface of endothelial cells and accelerate cell adhesion.
- 日本電気泳動学会の論文
日本電気泳動学会 | 論文
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