Membrane damage of liposome by streptolysin produced from group A, C and G streptococci.
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概要
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Hemolysin produced by group A, C and G streptococci causes membrane damage by a mechanism dissimilar to that of a streptolysin S (SLS). This result was confirmed by analysis of isoelectric point, hemolytic efficiency and destruction of liposomes by hemolysin. On the other hand, although SLS has been shown not to induce destruction of liposomes, K+ was lost from the liposomes after exposure to 100 HD50 of SLS. This result suggested not only that hemolysis induced by SLS involves colloid-osmotic processes but also that SLS is a poreforming toxin.
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