Restriction fragment length polymorphism analysis of HLA class II genes on a case of bone marrow transplantation with an unexpected mixed lymphocyte culture reactivity.
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概要
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Restriction fragment length polymorphism (RFLP) analysis was carried out in a case of bone marrow transplantation, in which a pair of serological siblings represented an unexpected MLC reactivity. The RFLP patterns detected using the probes consisted of HLA class II gene cDNA showed the differences between the donor and the recipient. The unexpected MLC reactivity observed between the donor and recipient with the identical serological HLA types appeared to be induced by the HLA class II disparities which was detectable by DNA analysis.
- 日本電気泳動学会の論文
日本電気泳動学会 | 論文
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