Polymorphism of the group-specific component in Japanese monkeys as revealed by two-dimensional gel electrophoresis.
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概要
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The polymorphism of group-specific component (Gc) in Japanese monkeys (Macaca fuscata fuscata) was analyzed by two-dimensional gel electrophoresis. Two phenotypes were detected by two-dimensional gel electrophoresis. These were designated as Gc 2 and Gc 2-2A1 according to the nomenclature described by Constans et al.1) in comparison with the phenotypes detected by convensional isoelectric focusing electrophoresis followed by immunofixation with anti-human Gc. The phenotype frequencies in ten wild Japanese monkeys were 70% for type Gc2 and 30% for type Gc2-2A1. The Gc typing in Japanese monkeys by two-dimensional gel electrophoresis is a useful and inexpensive method than convensional isoelectric focusing electrophoresis followed by immunofixation with antiserum.
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