Analgesic Effect of Combination of Iontophoresis of Lidocaine and Infiltration Intradermal Anesthesia with Very Fine Needle for Intravenous Injection.

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To reduce the pain of venipuncture we used a combination of iontophoresis of lidocaine and infiltration anesthesia with a very fine needle before venous puncture to obtain an analgesic effect around the vessel. We examined the analgesic effect of this method compared with the usual topical anesthesia of lidocaine. After obtaining informed consent, 20 healthy volunteers between the ages of 25 and 56 were studied. we chose both contralateral veins at the dorsal part of the hand or the cephalic vein at the wrist for venous puncture. We applied silicon-rubber frames packed with cotton fiber immersed in 10% lidocaine liquid on the skin over both veins. One side was the experimental site, where lidocaine iontophoresis was applied at the rate of one mA for ten minutes, and the opposite site was the control, where lidocaine iontophoresis was not applied. The sites using ionto-phoresis were allocated randomly to each hand. We performed a double-blind comparison in this study.The combination of 10% lidocaine iontophoresis and intradermal Prilocaine infiltration with a very fine needle provided effective skin analgesia for venipuncture. The mean VAS score (maximum: 100) of venipuncture was 11±16 SD (control: 20±23 SD) when using this method.
日本臨床麻酔学会の論文