Effects of MK 870 and Pteridine Derivatives on the Toad Bladder
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概要
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MK870 at a concentration of 1×10-7M was effective on the sodium transport of the urinary bladder of the toad. Triamterene and furterene were also effective at a concentration of 5×10-7 M. The effective concentrations of MK870 and pteridine derivatives were far lower than those of other diuretics and inhibitors, probably because the toad bladder is similar to the mammalian distal segment of the nephron.
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