A qualitative and quantitative study of few enzymes in the liver of cadmium fed rats.

概要

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Cadmium when administered to animals is known to accumulate in the liver and kidney, causing identifiable toxic effects. These effects on enzyme systems have been described in the present investigation selecting few of them viz. alkaline phosphatase, acid phosphatase, glucse-6-phosphatase and cholinesterase in the liver of rat, Rattus rattus albino. Topographical study on dysenzymia thus made have been found helpful in manifesting further the mechanism of Cd toxicity. Variations in the level of enzyme protein, state of cellular organelle together with processes of phosphorylation, adenylation and oxidative phosphorylation have been discussed explaining the cause and significance of these changes in enzyme activity.
独立行政法人労働安全衛生総合研究所の論文