A case of severe dehydration with marked rhabdomyolysis.
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A 23-year-old male was admitted to hospital with severe dehydration and hypokalemic myopathy due to secondary aldosteronism. Onadmissionserum sodiumand chloride were markedlyelevated to 198 mEq/1 and 169 mEq/1, respectively, and serum potassium was down to 2.3 mEq/1. Serum electrolytes were normalized by transfusion therapy, but subsequently rhabdomyolysis grew worse due to metabolic abnormalities such as dehydration, hypothermia, oppressive ischemia and metabolic acidosis, at the same time transient polyuria and the elevation of serum myoglobin and enzymesoriginating in muscle tissue were observed. Serum CPKwent up to 26, 532 IU/1 on the sixth day and other enzymes reached a peak following CPK. Dexamethasone was administered when the increase in enzyme levels caused the patient to fall into a stupor. Herapidly regained consciousness from the 15th day after admission, and he was able to stand up on the 29th day. Serumenzymes originating in muscle tissue decreased gradually to the normal range by the 30th day and no renal failure occurred.
- 社団法人 日本内科学会の論文
社団法人 日本内科学会 | 論文
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