A long follow up report of a patient with total pancreatectomy. The sequelae of long-standing diabetes.:The Sequelae of Long-Standing Diabetes

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There have been few reports of the sequelae of longstanding diabetes secondary to total pancreatectomy. This is a follow-up report of a patient who is still alive and reasonably well, after the removal of her whole pancreas because of chronic pancreatitis thirteen years ago. The daily insulin dose was 28 to 42 units of Rapitard insulin during the first few years, postoperatively and has been usually less than 20 units of MC semilente insulin in the last three years. Although she experienced ketoacidosis three years ago, the diabetes itself has been relatively stable with no severe hypoglycemic episodes. Evidence of peripheral neuropathy and retinopathy, presumably diabetic, developed eight years after total pancreatectomy. Persistent proteinuria and an ischemic lesion in the terminal part of the left little finger appeared ten years after operation. The patient, now seventy-five years old, is seen regularly as an outpatient and works as housewife.
社団法人　日本内科学会の論文