Detection of EBV RNA (EBER-1 and EBER-2) in Malaria Lymph Nodes by In Situ Hybridization

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概要

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• Acute Plasmodium falciparum malaria in African children allows expansion of latent Epstein-Barr virus infection, leading to colonization of lymph nodes by virus-infected lymphoblasts in 60% of cases as demonstrated by in situ hybridization for the detection of EBER-1 and EBER-2 RNA. This probably arises against a background of malaria-induced immunosuppression to EBV and concurrent lymphoid activation. The relevance of the results to the pathogenesis of African endemic Burkitt's lymphoma is discussed.

• 微生物学・免疫学学会連合の論文

微生物学・免疫学学会連合 | 論文

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