Effects of .BETA.1-4 Galactooligosaccharides Administration on Defecation of Healthy Volunteers with Constipation Tendency.

概要

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A questionnaire survey was conducted in 128 healthy volunteers with constipation tendency to study the effect of β1-4 linked galactooligosaccharides (4′-GOS) on defecation. The first group of 78 females were given the beverage containing 2.5 g /day or 5.0 g /day of 4′-GOS for one week and another group of 9 males and 41 females the beverage containing 10.0 g/day of 4′-GOS for one week. Responses were analyzed in respect of the 4′-GOS intake period and the nonintake period, and the following results were obtained.<BR>1) The defecation frequency (number of times/day) significantly increased while the subjects took the beverage with 5.0 g or 10.0 g of 4′-GOS (p<0.05). The number of days/week when they had defecation increased significantly during the intake period in all subjects in the 4′-GOS 10.0 g group (p<0.05) and in those with low defecation frequency in the 4′-GOS 5.0g group (p<0.01).<BR>2) Feces became significantly softer by drinking the beverage containing 5.0 g or 10.0g of 4′-GOS (p<0.05).<BR>3) The frequency of symptoms such as flatus and bowel movement increased by drinking the beverage containing 10.0 g of 4′-GOS (p<0.05).<BR>The results revealed that the beverage containing 5.0g or 10.0g of 4′-GOS improved defecation of persons with a tendency for constipation.
特定非営利活動法人日本栄養改善学会の論文