Clinical Results of Local Hyperthermia with Thermotron RF-8 for the Treatment of Prostatic Carcinoma and Prostatic Hyperplasia.

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The radiofrequency capacitive hyperthermia with Thermotron RF-8 was used for the treatment of prostate carcinoma and prostate hyperplasia. The subjects were 8 patients of prostatic carcinoma and 3 cases of prostatic hyperplasia at the Department of Urology Nagoya City University Medical School between July 1987 and August 1990. In the prostatic carcinoma group, the pathological diagnosis by needle biopsy was squamous cell carcinoma in one of the 8 patients and adenocarcinoma in 7. The clinical stage was T3 in 4 patients and T4 in 4. Hyperthermia was given once weekly, 2 to 10 times in total, by using a Thermotron RF-8. Radiation was used in combination with hyperthermia in 6 patients, and hormone drugs were administered to 7 patients except a patient with squamous cell carcinoma. In the prostatic hyperplasia group, hyperthermia was given to each patients 2 to 6 times. Hyperthermia resulted in PR in 5 of the 8 patients with prostatic cancer, MR in 2 and NC in one. Two of them are dead, and 5 surviving. The survival period ranged between one and 5 months. Improvement of dysuria and reduction in the prostate were achieved in all 3 patients with prostatic hyperplasia. As side effects, hyperthermia caused mild burns in one patient and fat induration in 3, but no serious conditions. Therefore, local hyperthermia with Thermotron RF-8 is very useful for the treatment of prostatic carcinoma and prostatic hyperplasia. However, examination of the prognosis of prostatic cancer necessitates a long-term followup, and patients with prostatic hyperpalasia must be followed up determine whether the reduction in the prostate is transient or permanent.
日本ハイパーサーミア学会の論文

Clinical Results of Local Hyperthermia with Thermotron RF-8 for the Treatment of Prostatic Carcinoma and Prostatic Hyperplasia.

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日本ハイパーサーミア学会 | 論文

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