Rupture risk ratio and annual rupture rate of unruptured cerebral aneurysms based on the data of aneurysmal subarachnoid hemorrhage.
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It has been said that the rupture rate of asymptomatic aneurysms is 1-2% per year. However, according to the recent International Study of Unruptured Intracranial Aneurysms, the rupture rate of small unruptured aneurysms was only 0.05% per year, and 0.5% per year for large (> 10 mm diameter) and all unruptured aneurysms inpatients who had subarachnoid hemorrhage (SAH) previously.<BR>During 1987-92 in Izumo City, Japan, Inagawa et al reported the age-and sex-adjusted annual incidence rate of aneurysmal SAH was 23-29 per 100, 000 population. Based on these data and those for published autopsy studies, the annual rupture rate of unruptured cerebral aneurysms was estimated. Rupture risk ratio (ruptured cerebral aneurysms/ruptured and unruptured cerebral aneurysms) stratified by age and location were calculated. Rupture risk ratio of anterior communication artery aneurysms was significantly higher than the other site of aneurysms. The annual rupture rate of unruptured cerebral aneurysms seems to be over 0.8 %per year. Whereas therewas no significant relationship between rupture risk ratio and age, both the incidence rate of aneurysmal SAH and the possible annual rupture rate increased with age. When we encounter patients with unruptured cerebral aneurysms, we should take into account that these lesions have relatively high risk for rupture.
- 一般社団法人 日本脳卒中学会の論文
一般社団法人 日本脳卒中学会 | 論文
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