The Effect of Active Vitamin D for Osteoporosis.
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概要
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There are many conservative therapies for patients with osteoporosis. We have treated them with active vitamin D and calcium, and evaluated their bone mass.The subjects consisted of one man and 30 women diagnosed with primary osteoporosis. All patients were treated with active vitamin D (alfacalcidol, 1α OHD3, 1μg/day) and calcium lactate (1-3g/day). Their mean age was 71 years (range: 51 to 84 years). The period of administration ranged from 1 year to 10 years with a mean of 4 years and 4 months. Patients were examined with the digital image processing (DIP) method.The mean ∑GS/D Values calculated using the DIP method were 2.04mmAl before treatment and 2.07mmAl at the follow-up, while there was no significant increase. There was no significant increase of bone mass at the follow-up in the patients whose ∑GS/D values before treatment were higher than 2.00. On the other hand, there was statistically significant increase of bone mass at the follow-up in the patients whoes ∑GS/D Values before treatment were lower than 1.99.We concluded that administration of active vitamin D was useful treatment for primary osteoporosis.
- 中国・四国整形外科学会の論文
中国・四国整形外科学会 | 論文
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