TETRAPLOID CHROMOSOME CONSTITUTION CHARACTERISTIC OF THE TUMOR CELLS OF THE TAKEDA SARCOMA
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概要
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The present paper describes the results of the karyological study of the tumor cells of the Takeda sarcoma in rats. It was found that there is present a strain (or strains) of tumor cells hoving a subtetraploid complex of chromosomes, and remaining unaltered in chromosome individuality through succesive transplant generations. The growth of the tumor is due primarily to the proliferation of these strain cells. The chromosome complex of the strain-cell consists of two distinct groups, namely a group of rod-shaped chromosomes and a group of V-, and J-shaped ones of varying sizes. Among the two-armed chromosomes, a large J-shaped chromosome, tripartite in structure, and a large V-shaped element, one or rarely two in number, are very prominent due to their outstanding size.
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