Genotyping of Pneumocystis carinii f. sp. hominis Isolates in Japan Based on Nucleotide Sequence Variations in Internal Transcribed Spacer Regions of rRNA Genes
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概要
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Genotyping of Pneumocystis carinii (Pc) isolated from 24 bronchoalveolar lavage (BAL) fluid specimens in Japan was examined based on nucleotide sequence variations in internal transcribed spacer regions 1 and 2 (ITS1 and ITS2, respectively) of rRNA genes. We found 11 ITS1 genotypes including 2 novel ones and 11 ITS2 genotypes including 3 new ones. Combining the ITS1 and ITS2 genotypes resulted in 30 ITS genotypes, of which 10 are newly described in this report. Two or more genotypes in ITS regions in a specimen were observed in 16 of 24 patients. Our results will be of help for the epidemiological investigation of Pc infection.
- 微生物学・免疫学学会連合の論文
微生物学・免疫学学会連合 | 論文
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