Localization of a Determinant Mediating Partial Macrolide Resistance in Staphylococcus aureus
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概要
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Four out of more than 8, 200 Staphylococcus aureus strains isolated in Japan between 1961 and 1980 were constitutively resistant to a variety of macrolide antibiotics except tylosin and rokitamycin, but susceptible to lincosamide and streptogramin type B antibiotics (PM). The data obtained by agarose gel electrophoresis, CsCl-ethidium bromide density gradient analysis, diagnosis with ATP-dependent deoxyribonuclease, and a test transducing into a rec- mutant with phage 80L2 propagated on PM-resistant S. aureus all suggested that the determinant for the PM-resistance is located in chromosome.
- 微生物学・免疫学学会連合の論文
微生物学・免疫学学会連合 | 論文
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