口腔内出血を契機に診断されたビタミンK 欠乏症の1例

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Vitamin K deficiency is an acquired condition associated with blood coagulation disorders. We describe our experience with a case of vitamin K deficiency.A 71-year-old man with an unusual oral hemorrhage who had a wound in his cheek came to our hospital. His medical history included cerebral infarction, cerebral hemorrhage, hypertension, and aspiration pneumonia treated by antibiotics. Oral intake of food was stopped to prevent aspiration pneumonia, and his only energy source was intravenous hyperalimentation.We suspected a blood coagulation disorder because of prolongation of APTT and PT, decreased thrombotest values, and elevated PIVKA-Ⅱ levels on peripheral blood testing. We therefore administered 10 mg of Menatetrenone (vitamin K) intravenously, and consulted with the Department of Hematology in our hospital. The Department of Hematology diagnosed vitamin K deficiency because of decreased Hepaplastin test values and decreased coagulation factor Ⅱ, Ⅹ, and protein C activation levels. These abnormalities were found to be caused by vitamin K deficiency on additional examinations. After vitamin K administration, no unusual oral hemorrhage occurred during hospitalization.
Japanese Society of Oral and Maxillofacial Surgeonsの論文