喉頭癌の腹腔内転移が疑われた悪性リンパ腫例

概要

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We report herein on a rare case of double primary malignant tumors composed of squamous cell carcinoma of the larynx and malignant lymphoma. The patient was a 60-year-old man with the chief complaints of swelling on the right side of his neck and hoarseness. Endoscopic examination demonstrated a massive tumor on the right supraglottic tissue. The accumulation of fluorodeoxyglucose was seen in the larynx, the cervical lymph nodes, the spleen, and the intraperitoneal lymph nodes. Supraglottic squamous cell carcinoma of the larynx (T4aN2bM1) was histologically diagnosed. As a treatment, chemotherapy was first performed. From the second course after inception of the administration, the intraperitoneal metastatic lesion almost disappeared on PET-CT, and furthermore, after the third course concurrent chemoradiotherapy was administered. As a result, the right supuraglottic tumor had completely disappeared. However, an intraperitoneal lymph node had developed. The patient underwent laparotomy, and investigation of the biopsy revealed an intraperitoneal tumor. The histopathological diagnosis was diffuse large B-cell lymphoma. The patient was treated with R-CHOP. There was no recurrence of laryngeal carcinoma observed for 9 months until he died of malignant lymphoma.