Real-world Experience of Carotid Artery Stenting in Japan: Analysis of 7,134 Cases from JR-NET1 and 2 Nationwide Retrospective Multi-center Registries
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概要
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The present study aimed to demonstrate the "real-world" experiences of carotid artery stenting (CAS) in Japan using Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2, retrospective nationwide multi-center surveillances. JR-NET1 and 2 registries are retrospective surveillances conducted between January 2005 and December 2007 and January 2008 and December 2009, respectively, in Japan regarding neuroendovascular therapy. A total of 7,134 procedures (1,943 for JR-NET1 and 5,191 for JR-NET2) were included in this study and retrieved data were analyzed retrospectively. Treatment results of two surveillance periods were similar. In JR-NET2 registry, total of 5,191 lesions were treated by CAS and 5,008 of 5,191 procedures (96.5%) were performed by the board-certified surgeons of Japanese Society of Neuroendovascular Therapy. The rate of technical success was extremely high (99.99%), and the rate of clinically significant complication was low (3.2%). These results were comparable to a previous large study in Japan. Multivariate logistic analysis revealed that age [odds ratio (OR), 1.04 per year; 95% confidence interval (CI), 1.02–1.07; p = 0.0004), symptomatic lesion (OR, 1.87; 95% CI; p = 0.0004), and the use of closed-cell type stent (OR, 0.58; 95% CT, 0.32–1.00; p = 0.05) were independently associated with clinically significant complications. It was revealed that good clinical results were achieved in patients who underwent CAS in Japan. It is expected that the evolution of devices and increasing experiences of surgeons would lead to further improvement of the clinical results, and further investigation would be required to clarify the optimal treatment strategy and therapeutic efficacy of CAS, especially in symptomatic lesions.
- 社団法人 日本脳神経外科学会の論文
著者
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Enomoto Yukiko
Department Of Chemistry Graduate School Of Science Osaka University
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Egashira Yusuke
Department Of Neurosurgery Gifu University Graduate School Of Medicine
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Sakai Nobuyuki
Department Of Applied Chemistry Faculty Of Engineering The University Of Tokyo
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Yoshimura Shinichi
Department of Molecular Life science (Cell Biology Division), Tokai University School of Medicine
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YOSHIMURA Shinichi
Department of Neurosurgery, Gifu University Graduate School of Medicine
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ENOMOTO Yukiko
Department of Neurosurgery, Gifu University Graduate School of Medicine
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