Major Dietary Patterns and Risk of Asymptomatic Hyperuricemia in Chinese Adults

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概要

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• In this study, we conducted a case-control study to evaluate the association of major dietary patterns and asymptomatic hyperuricemia taking account of blood lipids in Chinese adults. 187 cases with confirmed asymptomatic hyperuricemia and 187 controls were frequency matched on age, gender and area of residence. We conducted factor analysis using dietary information from a validated food frequency questionnaire to derive dietary patterns. The association between major dietary patterns and asymptomatic hyperuricemia was assessed by logistic regression analysis. Three major dietary patterns were found: 1) "animal products and fried food," 2) "western," 3) "soybean products and fruit." In multivariate analyses the "animal products and fried food" pattern score was associated with an odds ratio (OR) of 2.15 (95% CI, 1.22-3.76) compared with the lowest tertile. The OR for the top tertile of score for "soybean products and fruit" pattern was 0.32 (95% CI, 0.19-0.57) compared with the lowest tertile of "soybean products and fruit" pattern score. The significant association of these two patterns and asymptomatic hyperuricemia persisted after further adjusting for blood lipids. On the other hand, the "western" pattern was not associated with asymptomatic hyperuricemia. We observed a positive relationship between the "animal products and fried food" pattern and asymptomatic hyperuricemia, and a negative relationship between the "soybean products and fruit" pattern and asymptomatic hyperuricemia, independent of blood lipids.

• 財団法人 学会誌刊行センターの論文

著者

• HUANG Guowei

  Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University

• Chang Hong

  Department Of Hematology West China Hospital Sichuan University

• WANG Xuan

  Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University

• ZHANG Meilin

  Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University

• GAO Yuxia

  Department of Cardiology, General Hospital of Tianjin Medical University

• XU Weili

  Department of Epidemiology, School of Public Health, Tianjin Medical University

• LIU Dongmei

  Health Examination Center of Heping District

• LI Guangjing

  Health Bureau of Heping District

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