Application of Response Surface Methodology (RSM) to the Assay of Lactate Dehydrogenase (LD)

スポンサーリンク

概要

• 論文の詳細を見る

• We examined the reaction surfaces around two variables (lactate and NAD<SUP>+</SUP>) in the JSCC (Japan Society of Clinical Chemistry) method for determining Lactate dehydrogenase (LD), using 23 factorial experimentation at the reaction temperatures of 30 and 37°. Theoretical response surfaces were computed by fitting a quadratic polynomial equation to the experimental data by least-squares regression. Our response surface data showed a broad plateau over the concentration range investigated (lactate 5-210 mmol/L, NAD<SUP>+</SUP> 1-19 mmol/L, respectively ). Response surface methodology (RSM) is a collection of statistical and mathematical techniques useful for developing, improving and optimizing processes.

• Japan Society of Clinical Chemistryの論文

著者

• 平野 哲夫

  東京警察病院臨床検査第1部

• 平野 哲夫

  東京警察病院

• 岩崎 学

  成険大学理工学部情報科学科

関連論文

• 各種肝症患における抱合ビリルビン値測定の意義
• Excel による応答曲面法(RSM)の解析(II)
• Excel による応答曲面法(RSM)の解析
• P-181 ワルファリン投与と血液凝固能との時間的関係に関する実態調査
• 免疫グロブリン測定における低濃度測定値の信頼性
• 乳酸デヒドロゲナーゼ(LD)活性測定の至適条件の Response Surface Methodology (RSM) の応用の試み
• Analysis of response surface methodology using Excel (II)
• Investigation of the Optimum Conditions for Measurement of Human Lactate Dehydrogenase Activity
• Application of Response Surface Methodology (RSM) to the Assay of Lactate Dehydrogenase (LD)
• Multiformity of Sugar Chain(s)in Tumor-Associated CEAs Detected by Lectin Affinity Chromatography
• Clinical and Enzymological Studies on Human Lactate Dehydrogenase:I. Two Km Values of Serum LDH for Lactate
• 酵素法による1,5AG測定の基礎的検討および臨床的有用性

もっと見る 閉じる

スポンサーリンク