Cardiac Event Rate in Hypertrophic Cardiomyopathy Patients

概要

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Background: ICD implantation can prevent sudden cardiac death (SCD) in high risk hypertrophic cardiomyopathy (HCM) patient. However, selecting patient to receive an ICD for primary prevention is challenging. ICD implantation also carries some risks. Aim: The aims of this study: (1) To evaluate the incidence of VT, VF in HCM patients. (2) To evaluate the mean time duration to the first appropriate shock. (3) To evaluate the incidence of inappropriate shock. Method: Retrospective analysis from the registry of ICD implantations for 51 HCM patients over the past 10 years in IJN with 35 primary preventions (group 1) and 16 secondary prevention (group 2). Results: Mean follow up duration time in group 1: 44±33.6 mths, 6 patients developed VT with appropriate shock (17%), mean duration time to first shock: 34.7±21.9 mths, 2 patients developed electrical storm (5.7%). In group 2 with follow up duration: 38.40+28.8 months, 9 patients developed VT with appropriate shock (56%), mean duration time to first shock: 5.76+6.24 months, 5 patients developed electrical storm (31%). No patient developed VF. Conclusion: Although the number of patient is rather small but with good follow up duration, the study demonstrated high incidence of VT in primary group. Secondary group had higher incedence and shorter duration time to develop event.