The Effects of Brachial Arterial Stiffening on The Accuracy of Oscillometric Blood Pressure Measurement: A Computational Model Study
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概要
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Oscillometric noninvasive blood pressure measurement (ONBPM) is nowadays widely applied in health care. However, ONBPM has been found to exhibit large interindividual variability in accuracy. In the present study, we developed a theoretical model to describe the mechanics of the brachial arterial wall and particularly arterial stiffening dominated respectively by wall thickening and elastin degeneration. The model was incorporated into a cardiovascular-cuff model to investigate the effects of brachial arterial stiffening on the accuracy of ONBPM. It was found that wall-thickening-dominated arterial stiffening induced overestimate of the systolic pressure, whereas the elastin-degeneration-dominated arterial stiffening induced overestimate of both the systolic pressure and the diastolic pressure. The findings support the clinical observation that pseudo-hypertension is more prevalent in the elderly, and at the same time imply that arterial stiffness indices (e.g., compliance of artery, pulse wave velocity) assessed under the physiological pressure (generally between 70 and 150mmHg) conditions may be insufficient for assessing the accuracy of ONBPM.
- 一般社団法人 日本機械学会の論文
著者
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Takagi Shu
Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Bunkyo, Tokyo 113-8656, Japan
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LIU Hao
Graduate School of Engineering, Chiba University
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LIANG Fuyou
Computational Science Research Program, RIKEN
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