Measurements of the driving forces of bio-motors using the fluctuation theorem

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概要

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• The fluctuation theorem (FT), which is a recent achievement in non-equilibrium statistical mechanics, has been suggested to be useful for measuring the driving forces of motor proteins. As an example of this application, we performed single-molecule experiments on F1-ATPase, which is a rotary motor protein, in which we measured its rotary torque by taking advantage of FT. Because fluctuation is inherent nature in biological small systems and because FT is a non-destructive force measurement method using fluctuation, it will be applied to a wide range of biological small systems in future.

著者

• Hayashi Kumiko

  Department Of Physics Waseda University

• Kishikawa Jun-ichi

  Department Of Bioscience And Bioinformatics Kyushu Institute Of Technology

• Tanigawara Mizue

  School of Frontier Bioscience, Osaka University

• Kishikawa Jun-ichi

  Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University

• Hayashi Kumiko

  Department of Applied Physics, School of Engineering, Tohoku University

関連論文

• The cytochrome bcc-aa3-type respiratory chain of Rhodococcus rhodochrous
• Fluctuation Theorem Applied to Dictyostelium discoideum System
• Correlation Between Proton Translocation and Growth : Genetic Analysis of the Respiratory Chain of Corynebacterium glutamicum
• Measurements of the driving forces of bio-motors using the fluctuation theorem

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