CLINICAL AND EXPERIMENTAL STUDIES ON A SIMPLE ALKALINE THERMAL:PART I Clinical Study
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概要
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A) The effect of simple alkaline thermal bath on serum cholinesterase (Ch-E) activity in rheumatoid arthritis:Serum Ch-E activity in rheumatoid arthritis was measured once a week in National Hospital at Spa Itoh, before, 30, 60, and 120min. after a daily thermal bath at 41°C for 10min.1) Serum Ch-E activity in rheumatoid arthritis showed lower values than that of the healthy control, and the more the stage of the disease progressed, the lower the Ch-E activity decreased.2) Effect of a thermal bath at 41°C for 10min.A slight increase in Ch-E activity was observed after bathing in the healthy control, and similar tendency was observed in cases in the Stage I and II. But a marked decrease was proved in cases in Stage III on the contrary.3) Effect of a series of thermal baths, once a day at 41°C for 10min.:Eleven out of fourteen subjects showed an increase in amplitude or an inversion of type of fluctuation in Ch-E activity following thermal bath between the 4-14th day of Spa treatment.Such a fluctuation in biological reaction occured earlier in patients, whose therapeutic results proved better than others.Serum Ch-E activity before bathing showed maximum fluctuation in the 2. -3. week. But no constant tendency in the direction of fluctuation was observed. In healthy subjects, Ch-E activity decreased gradually in the 2, -3. weeks, and then returned to the former level.Ch-E activity before bath, in patients in Stage II and III, which was decreased below normal range, showed an increase remarkably in 2 weeks, then returned to the initial level after 4 weeks.There was observed a normalisation of Ch-E activity in cases, whose former values proved lower than normal, through the course of a series of thermal baths at 41°C for 10min.B) The effect of simple alkaline thermal bath at Itch Spa on the blood pressure:Blood pressure of in-patients of National Hospital at Itoh was measured before, 15, 30, 45, 60, 90, and 120min. after bathing at 39°C for 20min. respectively. Results obtained from this observation are as follow:1) Effect of a single bath at 39°C for 20min.:Systolic pressure:A group of patients with systolic pressure over 150mm/Hg showed an average fall of 16mm, 15min. after bathing, and this decrease in the blood pressure continued up to 120min. after bathing.A group of patients with systolic pressure of 130-149mm/Hg showed an average fall of 6mm 30min. after bathing, then this fall recovered towards 60min., and returned to the former level 120min. after bathing.A group of patients with systolic pressure less than 129mm/Hg showed a rise of 3mm/Hg in an average after 15min., then decreased gradually towards 60min., and returned to the former level 120min. after bathing.Diastolic pressure:Diastolic pressure showed similar change as systolic pressure, but not so remarkably.Pulse amplitude:In relatively hypertensive group, pulse amplitude decreased after 15min. and the decrease continued till 120min. after bathing.In relatively hypotensive group, pulse amplitude increased after 15min., then returned to the former level gradually.2) Effect of a series of baths once a day at 39°C for 20min.:As the number of patients studied were so few, no definite conclusion was drawn concerning the effect of a series of thermal baths on the blood pressure.
- 一般社団法人 日本温泉気候物理医学会の論文
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