ON GASTRIC CORPUS-PYLORIC ANTRUM INHIBITORY REFLEXES
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Twenty eight adult dogs fasted over night were used under Nembutal anesthesia. The influences of distension of the pouch which was made on gatric corpus on the motility of gastric pyloric antrum were investigated. The following results were obtained.<BR>1) Any changes were not observed on the motility on gastric pyloric antrum by distension of gastric corpus pouch by a pressure of 20mmHg, but a stepwise elevation of the lumen pressure of the pouch from 50mmHg to 100mmHg elicited a remarkable relaxation of the tone and inhibition of motility of the pyloric antrum. These inhibitory responses were not abolished by the bilateral cervical vagotomy or by the bilateral splanchnicotomy respectively, but these inhibitory reflexes were disappeared completely after the transection of both extrinsic nerves.<BR>2) The inhibition of motility of gastric pyloric antrum were also elicited by the electric stimulation of the central cut end of vagal branch or of splanchnic branch which innervated the gastric corpus respectively.<BR>3) It may be concluded that the reflex pathways of the gastric corpus-pyloric antrum inhibitory reflexes involve not only in vagus nerves but also in splanchnic n erves.
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