Arachnoid Cysts and Epilepsy in Children: The Relationships betwen EEG Findings and Cyst Locus and Volume.:The Relationships between EEG Findings and Cyst Locus and Volume

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In order to elucidate the pathophysiology of epilepsy with intracranial arachnoid cysts, we studied the relationships between encephalographic findings and the location the volume of arachnoid cysts.<BR>Subjects in this study were thirty-three patients (27 males and 7 females, ranging in age from O month to 13 years (4.0±4.2 years)) with primary intracranial arachnoid cysts. Cases with secondary arachnoid cysts and cases involving arachnoid cystectomy were excluded. Cysts were located in the middle cranial fossa in 21 cases, in the supratentorial location other than the middle cranial fossa in 4 cases, and in the infratentorial area in 8 cases. EEG abnormalities were observed in 21 cases, out of which 11 cases (the epileptic group) exhibited epileptic seizures (partial seizures, 7 cases; generalized seizures, 4 cases). Among the cases of cysts in the infratentrial area, 2 cases showed partial seizures and focal spikes in their EEGs. The volume of arachnoid cysts was significantly larger in the non-epileptic group with EEG abnor-malities than in the epileptic group (p<0.03).<BR>Our study suggests that the epilepsy seen with arachnoid cysts is not directly caused by the cysts perse. Cerebral lesions accompanying arachnoid cysts may partici-pate in the development of epilepsy.
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