Mechanism of the carboxylation of cyclohexanone with carbon dioxide catalyzed by 1,8-diazabicyclo[5.4.0]undec-7-ene.
スポンサーリンク
概要
- 論文の詳細を見る
The dependence of the rate of carboxylation upon the concentration of the reactant was investigated in dimethyl sulfoxide. The reaction rate depended upon the concentration of cyclohexanone and 1,8-diazabicyclo[5.4.0]undec-7-ene(DBU) in the first order, respectively. The reaction also followed first-order kinetics regarding the CO<SUB>2</SUB> pressure in the range 50–400 Torr. From these reaction characteristics, it is suggested that carboxylation proceeds via a reaction between CO<SUB>2</SUB> dissolved in dimethyl sulfoxide and the anion of cyclohexanone, rather than between the CO<SUB>2</SUB> adduct with DBU and cyclohexanone. The results of carboxylation by the CO<SUB>2</SUB> adduct with DBU and by CO<SUB>2</SUB> dissolved in dimethyl sulfoxide also support the above conclusion. The formation of the cyclohexanone anion by a reaction of cyclohexanone with DBU was verified by the UV spectrum of a solution of concentrated DBU and cyclohexanone.
- 公益社団法人 日本化学会の論文
著者
関連論文
- Determination of Isocitrate Using Immobilized Isocitrate Dehydrogenase in a Flow System and its Application to Analyze the Total Isocitrate Content of Beverages
- Determination of the Inorganic Phosphorus Content in Serum by the Use of Immobilized Enzyme Reactions in an FIA System
- Determination of Glucose in Plasma Using Immobilized Enzymes in a Flow System
- Determination of L-Malate Using Immobilized Malate Dehydrogenase and Aspartate Aminotransferase in a Flow System and its Application to Analyze the L-Malate
- Simultaneous Determination of Ethanol and Acetaldehyde in Liquor Using a Flow System Composed of Two Enzyme Reactors and an Octadecylsilica Column
- Glucose Determination Using a Flow System with Enzyme Reactor and Application to Analysis of Glucose Content in Beverages
- Determination of D-Malate Using Immobilized D-Malate Dehydrogenase in a Flow System and its Application to Analyze the D-Malate Content of Beverages
- Determination of Acetaldehyde Using Immobilized Aldehyde Dehydrogenase in a Flow System and Application to Analysis of Acetaldehyde Content in Liquors
- Direct Determination of Nitrate Using Nitrate Reductase in a Flow System
- Determination of Formate Using Immobilized Formate Dehydrogenase in a Flow System and Its Application to Analyze the Formate Content of Foodstuffs
- Determination of Nitrate in Biological Fluids Using Nitrate Reductase in a Flow System
- Mechanism of the carboxylation of cyclohexanone with carbon dioxide catalyzed by 1,8-diazabicyclo[5.4.0]undec-7-ene.
- Fluorometric Determination of Amino Acids and Proteins Utilizing a Copper(II) Catalyzed Reaction.