The Reaction of Nitriles under High Pressure. III. The Cyclotrimerization of Aliphatic Nitriles in the Presence of Alcohols and the Rearrangement of the Resulting Trialkyl-1,3,5-triazines to 4-Aminopyrimidines

スポンサーリンク

概要

• 論文の詳細を見る

• The examination of the simultaneous formation of symmetrically tri-substituted 1,3,5-triazines, 4-amino-2,5,6-substituted pyrimidines and <I>N</I>-pyrimidylamidines in mixtures of lower alcohol and nitrile with more than two hydrogen atoms on the α-position under pressures of a few thousand atm afforded the following information: (1) the triazine is formed by the cyclo-trimerization of the iminoether which is derived from the nitrile and the alcohol; (2) the pyrimidine is formed by the rearrangement of the previously-formed triazine. This rearrangement is caused by an attack of the nucleophilic iminoether on a carbon atom of the triazine ring; and (3) the amidine is assumed to be formed, together with the pyrimidine, by the same attacking mechanism.

• 公益社団法人 日本化学会の論文

著者

• Yanagiya Koshin

  6th Division, National Chemical Laboratory for Industry

• Yasumoto Masahiko

  6th Division, National Chemical Laboratory for Industry

• Kurabayashi Masahiro

  6th Division, National Chemical Laboratory for Industry

関連論文

• The Reaction of Nitriles under High Pressure. II. The Catalytic Effects of Amines and Water on the Formation of Trisubstituted 1,3,5-Triazines from Nitriles
• The Reaction of Nitriles under High Pressure. III. The Cyclotrimerization of Aliphatic Nitriles in the Presence of Alcohols and the Rearrangement of the Resulting Trialkyl-1,3,5-triazines to 4-Aminopyrimidines
• The Reaction of Nitriles under High Pressure. IV. The Replacement of the Substituents of Trialkyl-1,3,5-triazines

スポンサーリンク