A Study of the Molecular Compound between Inosine and Tryptophan

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概要

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• Equilibria have been determined at 30 °C for the inosine-L-tryptophan–water and inosine–D-tryptophan–water systems. They show the formation of a molecular compound, which was demonstrated in U.S. Patent 3532684, over a wide range of variable ratios of the two components, inosine and tryptophan. The influence of some organic solvents on the formation of the molecular compound was examined, and it was shown that the water molecule is significantly involved in the formation of the crystalline molecular compound, and that solvent interactions play an important role. Similar crystalline molecular compounds were not formed by chemically closely related substances; the high specificity of the interaction between inosine and tryptophan was confirmed.

• 公益社団法人 日本化学会の論文

著者

• Hara Kentaro

  Central Research Laboratories, Ajinomoto Co., Inc.

• Suzuki Yoshihisa

  Central Research Laboratories, Ajinomoto Co., Inc.

• Hirahara Tsuneo

  Central Research Laboratories, Ajinomoto Co., Inc.

関連論文

• Polymorphism of Inosine. III. The Equilibrium for the Inosine–Dimethyl Sulfoxide–Water System
• A Study of the Molecular Compound between Inosine and Tryptophan
• Some Properties of the Salt between Inosine and L-Lysine
• The Formation of Crystalline Complexes between Inosine and Several Hydroxybenzoic Acids
• The Formation of Crystalline Molecular Complexes between Inosine and Several Phenols
• The Isomerization of Purine Nucleosides in a Dilute Alkaline Solution

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