脳内出血で発症した転移性extraskeletal myxoid chondrosarcomaの1例

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概要

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• The 59-year-old woman visited our hospital in ambulance because of drowsiness and nausea, Plain CT scan demonstrated mass lesion in the left occipito-parietal region accompanied with hemorrhage and rupture to the ventricle. Chest radiograph showed multiple mass lesions in bilateral lung fields. T1-weighted MR image of the pelvis after administration of contrast medium showed multiple heterogeneously enhanced mass lesions adjacent to the right femur. After the admission her consciousness level was going down day by day and then the emergent operation of resection of brain tumor was done. Histologically the brain tumor showed quite compact cellular feature with hemorrhage that was composed of large cells with vesicular nuclei, prominent nucleoli, frequent mitotic figures and deeply eosinophilic cytoplasm. Some of the tumor cells had glassy cytoplasmic inclusion bodies, indicating rhabdoid feature. Then, the differential diagnoses of the brain tumor were extrarenal malignant rhabdoid tumor, epithelioid sarcoma(proximal type), synovial sarcoma, malignant mesothelioma, extraskeletal myxoid chondrosaroma and so on. Thereafter, the biopsy of the tumor of the right thigh was done. The histology showed characteristic nodular configuration in which short anastmosing cords of eosinophilic tumor cells are deposited in abundant myxoid stroma. This lesion was diagnosed as extraskeletal myxoid chondrosarcoma and considered as the primary lesion and to be metastasized to the brain through the lung with dedifferentiation.

著者

• 小林 晏

  医療法人橘会 東住吉森本病院 病理科

• 寺川 雄三

  医療法人橘会 東住吉森本病院 病理科

• 山縣 徹

  医療法人橘会 東住吉森本病院 病理科

• 中西 愛彦

  医療法人橘会 東住吉森本病院 病理科

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• 脳内出血で発症した転移性extraskeletal myxoid chondrosarcomaの1例

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