糖尿病時の高エネルギー燐酸化合物代謝
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概要
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Blood level of ATP was estimated as the increase in organic phosphorus following seven minutes' hydrolysis as reported previously. <BR>Blood level of ATP was frequently decreased in uncontrolled diabetics. <BR>More marked decrease in ATP was found in juvenile diabetics and in diabetics with high fasting blood sugar level. <BR>The increase in blood ATP and decrease in inorganic phosphorus following glucose tolerance test was found to be less in uncontrolled diabetics compared with normal adults. <BR>A similar tendency was observed following fructose loading. <BR>Insulin treatment caused an increase in blood ATP, while sulfonylureas often failed to increase blood ATP even in cases showing satisfactory decrease in urinary sugar.
- 一般社団法人 日本内分泌学会の論文