Admission Levels of C-Reactive Protein and Plasminogen Activator Inhibitor-1 in Patients With Acute Myocardial Infarction With and Without Cardiogenic Shock or Heart Failure on Admission
スポンサーリンク
概要
- 論文の詳細を見る
Scarce data exist on the relationship of C-reactive protein (CRP) or plasminogen activator inhibitor-1 (PAI-1) to the occurrence of heart failure (HF) or cardiogenic shock (CS) after acute myocardial infarction (AMI) and on the relationship between these biomarkers and mortality in CS patients. Thus, we compared high-sensitivity CRP and PAI-1 antigen plasma levels on admission among 3 age- and gender-matched AMI patients groups (consisting of 60 patients with CS, 60 with HF, and 60 without HF on admission), after determining that PAI-1 levels did not vary significantly diurnally in these groups by comparing the data among subgroups which were divided according to admission time within the groups. For CS patients, we also conducted regression analyses to examine the relations of these biomarkers to mortality. CRP levels both in CS (P < 0.001) and HF (P < 0.05) patients were significantly higher compared to those without HF, PAI-1 levels in CS patients were significantly higher compared to both those with (P < 0.05) and without HF (P > 0.01), and CRP and PAI-1 were independent predictors of in-hospital (Odds ratio [OR] = 6.12, 95% confidence intervals [95%CI] = 1.47-25.54 and OR = 5.92, 95%CI = 1.31-26.77, respectively) and 1-year mortality (OR = 5.53, 95%CI = 1.21-25.17 and OR = 5.48, 95%CI = 1.09-27.52, respectively) in CS patients. In conclusion, at admission, CRP is associated with the occurrence of CS and HF and PAI-1 is associated with the occurrence of CS after AMI, and they are of prognostic value in CS complicating AMI.
- International Heart Journal刊行会の論文
著者
-
Akkus Mehmet
Department Of Cardiology Mersin University School Of Medicine
-
Sucu Nehir
Department Of Cardiovascular Surgery Mersin University Medical School
-
Cicek Dilek
Departments Of Cardiology Faculty Of Medicine Mersin University
-
Doven Oben
Department Of Cardiology Mersin University School Of Medicine
-
Yurtdas Mustafa
Department of Cardiology, Faculty of Medicine, Mersin University
-
Akcay Burak
Department of Cardiology, Faculty of Medicine, Mersin University
-
Polat Gurbuz
Department of Clinical Biochemistry, Mersin University School of Medicine
-
Ercetin Neslihan
Department of Clinical Biochemistry, Mersin University School of Medicine
関連論文
- Endothelin-1 and Nitric Oxide Concentrations and Their Response to Exercise in Patients With Slow Coronary Flow
- Cyanotic Tetralogy of Fallot With Its Infective Endocarditis Complication on the Tricuspid and Pulmonary Valves of a 55-Year-Old Man
- N-Acetylcysteine for Preventing Pump-Induced Oxidoinflammatory Response During Cardiopulmonary Bypass
- Endothelin-1 and Nitric Oxide Levels in Patients With Mitral Annulus Calcification
- A Case of Coronary Spasm with Resultant Acute Myocardial Infarction: Likely the Result of an Allergic Reaction
- Angiographic and Clinical Outcome Following Sirolimus-Eluting Stent (Cypher) Implantation A Single Center Experience:A Single Center Experience
- Admission Levels of C-Reactive Protein and Plasminogen Activator Inhibitor-1 in Patients With Acute Myocardial Infarction With and Without Cardiogenic Shock or Heart Failure on Admission
- Angiographic and Clinical Outcome Following Paclitaxel-Eluting Stent (Taxus) Implantation A Single Center Experience:A Single Center Experience
- Direct Stenting Versus Predilatation and Stenting Technique When Using Paclitaxel-Eluting Stents
- Diffuse Intimal Thickening of Coronary Arteries in Slow Coronary Flow.
- Early and Late Angiographic and Clinical Outcome Following Helistent Stent Implantation:A Single Center Experience