担癌動物における脾臓内T細胞と胸腺細胞の変動について
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概要
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Thirty thousand cells of sarcoma 180 were implanted on the back of C<SUB>3</SUB>H mice. The rejecting ability against implanted tumor was observed at the 14 th day after the primary tumor implantation (it is known as concomitant immunity) . This phenomenon depends on increase of T-lymphocytes in spleen with decrease of thymocytes. The re-implanted tumor began to grow at three weeks after surgical removal of the primary tumor. However, the reimplanted tumor never began to grow for a long time after irradiation of the primary tumor.<BR>It is suggested that increase of T-lymphocytes in spleen is related to the rejecting ability against re-implanted tumor growth and continuous existence of small amount of antigen sustains host immunity for a long time.
- 学校法人 昭和大学・昭和医学会の論文
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