走査型電子顕微鏡による膝半月板の観察--主として線維構造と変性の進行について
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概要
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Few reports on a architecture and degneration of semilunar cartilage have been studied using scanning electron microscopy (SEM) .<BR>The anther observed the architecture of the semilunar cartilage by its surface and cross section using SEM and studied about the change with aging, especially how degeneration progresses at each part of the semilunar cartilage.<BR>Discoid, injuried, deformed and regenerated meniscuses were also studied with the aid of light microscopy.<BR>These materials used in this experiment are 40 in total, ranging in age from 3 to 72 years.<BR>Ten were obtained from the disturbed semilunar cartilages removed at operation and 18 from injuried.<BR>Five were obtained from amputated legs, 4 from patients with arthropathy, 2 from autopsied legs and 1 from regenerated semilunar cartilage.<BR>The results obtained from the observation are summarized as follows.<BR>1) Three dimentional fibrous distribution was involved in the architecture of the semilunar cartilage. Main fibers were arranged in the horizontal direction. The fibers of the surface layer showed parallel arrangement which was thought to be a rational reason for the joint structure.<BR>2) The surface layer of the semilunar cartilage from younger human showed round prominences arranged connectedly at the inner edge and covered with aging became remarkable over 30 years of age.<BR>Physiological exhaustion was not related to the architecture of the semilunar cartilage, but non-physiological overweight influenced the progress of its degeneration.<BR>3) The way how degeneration progresses at each part of the semilunar cartilage was related to the movement of the joint.<BR>The degeneration of the semilunar cartilage facing the legs progressed more rapidly than that facing the thighs.<BR>The outer part and the inner part were degenerated rapidly in the surface layer and in the middle layer, respectively.<BR>In the inner part the middle to posterior segment and in the outer part the posterior segment were degenerated rapidly.<BR>4) In the discoid meniscus, the degeneration was marked in the middle segment of incomplete discoid and in the center part of complete discoid, and degeneration was prominent in the middle layer rather than in the surface layer.<BR>5) When the normal semilunar cartilage was injuried, the injury showed parallel running of fibers in many cases, and the degenration was limited to the fragmented parts and that by fragmentation.<BR>6) Degeneration in arthropathy was most remarkable and its picture showed combined feature of physiological mechanical degeneration and inflammatory degeneration.<BR>7) The structure of the surface layer in the regenerated semilunar cartilage was similar to the normal fibrous structure, but different from that of physiological semilunar cartilage.
- 学校法人 昭和大学・昭和医学会の論文