アンモニアの家兎脳血管に及ぼす作用に対する種々アスパラギン酸塩の影響
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概要
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The action of NH<SUB>4</SUB>Cl on the cerebral circulation and the effects of sodium, magnesium or potassium aspartate on the ammonia action in the cerebral circulation were studied and the following results were obtained.<BR>1) When NH<SUB>4</SUB>Cl was injected into vein, the blood pressure (BP) was decreased temporarily while no effects were observed in the cerebral blood flow (CBF) and the cerebral vaso-resistance (CVR) .<BR>2) When NH<SUB>4</SUB>Cl was injected into artery, BP was decreased temporarily and CBF was increased while CVR was decreased.<BR>3) The decrease of CVR caused by the intravenous injection of NH<SUB>4</SUB>Cl was inhibited by the premedication of sodium, magnesium or potassium aspartate.<BR>4) The increase of NH<SUB>3</SUB>level in blood caused by the intravenous injection of NH<SUB>4</SUB>Cl was inhibited by the premedication of sodium, magnesium or potassium aspartate.
- 昭和大学・昭和医学会の論文