実験的大動脈縮窄の血行力学的研究

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概要

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• "Atypical-coarctation of aorta"is used more in Japan than in the other country. The arm blood pressure was different from that of lower leg in it.<BR>Hemodynamic study was performed with dog experimentation and model experiment.<BR>Artificial coarctation was made with beneer band on the descending aorta in the chest of dog, on the abdominal aorta above and below renal artery.<BR>Each pressure above and below the aortic coarctation was recorded. Especially, beneer band was kept regular space.<BR>Being influenced by coarctation, heart function changed variously. Intracardiac pressure and the first delivative value with calibration was measured in left ventricle.<BR>Measurement of calibrated pressure curves revealed that reduction at external aortic round which was greater than 26 to 35 per cent was required to produce any changes in arterial pressure. The effects of successively greater reductions on systolic, diastolie and pulse pressure, and the first delivative value, above and below, the constriction were conveniently summerized.<BR>In perfect occulusion, the mean of systemic pressure was 226 mmHg, diastolic pressure was 127 mmHg, and the first delivative value was 1669 mmHg/sec.<BR>Systemic pressure and the first delivative value in left ventricle were rapidly elevated at external aortic round which was greater than 36 to 45 per cent.<BR>Ejection sound in vascular murmur was producted any changes with the progress of coarctation. The first murmur was greater than 16 to 25 per cent at region of coarctation.<BR>In model experimentation, Reyneld's number and amplitude of murmur did not paralleled at all, however murmur was appeared on Reyneld's number 60000.

• 学校法人 昭和大学・昭和医学会の論文

著者

• 松下 功

  昭和大学医学部外科学教室

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