CHANGES OF CEREBRAL BLOOD FLOW VELOCITY AT THE MIDDLE CEREBRAL ARTERY IN DIFFERENT PLACING RATES-Using Transcranial Color Doppler Imaging- : —Using Transcranial Color Doppler Imaging—

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We investigated the effects of different pacing rates (before pacing, 60, 80, 100 /min) on cerebral blood flow and hemodynamics in 5 patients (mean age 61.4 years) with a VVI pacemaker. We measured the cerebral blood flow at the middle cerebral artery using transcranial color Doppler imaging. We compared several pacing rates to hemodynamics such as stroke volume and cardiac output, as well as the cerebral blood flow velocity [maximum (Vmax), minimum (Vmin), and mean (Vmean) blood flow velocity] . Vmax was 0.9 ± 0.3 m/sec before pacing, and incrementally 1.2 ± 0.3 m/sec at 60 /min, 1.0 ± 0.3 at 80 /min, 0.9 ± 0.3 m/sec at 100 /min. Vmin was 0.3 ± 0.1 m/sec before pacing, 0.5 ± 0.2 m/sec at 60 /min, 0.4 ± 0.1 at 80 /min, 0.4 ± 0.1 m/sec at 100 / min. Vmean was 0.5 ± 0.1 m/sec before pacing, 0.7 ± 0.2 m/sec at 60/min, 0.6 ± 0.2 m/sec at 80 /min, 0.6 ± 0.1 m/sec at 100 /min. Stroke volume was 101.1 ± 27.3 ml before pacing, 119.1 ± 20.4 ml at 60 /min, 110.7 ± 18.0 ml at 80 /min, 104.3 ± 19.7 ml at 100 /min. Cardiac output was 4.0 ± 1.1 1/min at before pacing, 7.1 ± 1.21/min at 60 /min, 8.9 ± 1.9 1/min at 80 /min, 10.4 ± 2.01/min at 100 /min (p<0.05-P<0.01) . Blood flow velocity of the middle cerebral artery regarding stroke volume, Vmax, Vmin and Vmean was the highest at a pacing rate of 60 / min. From the results shown above, we conclude that the pacing rate of 60 /min gives the highest SV value, as well as the highest Vmax, Vmin, and Vmean values on blood flow velocity of the middle cerebral artery. Transcranial color Doppler imaging is non-invasive and a useful tool for observing changes of cerebral blood flow velocity at different pacing rates in patients with bradycardia necessary for cardiac pacing.

CHANGES OF CEREBRAL BLOOD FLOW VELOCITY AT THE MIDDLE CEREBRAL ARTERY IN DIFFERENT PLACING RATES-Using Transcranial Color Doppler Imaging- : —Using Transcranial Color Doppler Imaging—

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