レ線所見より見た小児副鼻腔炎の塩化リゾチ-ム(Neuzyme)大量療法の効果

概要

論文の詳細を見る
Massive dose of lysozyme was administered in 20 patients with infantile (younger than 15 y. o.) chronic sinusitis and the effect was mainly analyzed by x-ray findings of the paranasal sinuses. The dose of administration was 180mg/day for younger than 12 y. o. and 270mg/day for elder than the above age, and the mean duration was 40 days. As the results, subjective complaints, local findings of nasal cavities and x ray findings of the paranasal sinuses were improved in 70% of the patients. Therefore, it was concluded that massive dose administration of lysozyme would be effective for infantile chronic sinusitis. However, the authors emphasized that maintenance of the therapeutic effect had to be proven by prudent following-up studies.
耳鼻咽喉科臨床学会の論文