Pulmonary Function in Patients with Chronic Sinusitis.

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Sinobronchial syndrome (SBS) is a clinical entity which combines chronic sinusitis (CS) and various bronchial disorders: bronchiectasis, chronic bronchitis and diffuse panbronchiolitis.In the past, CS was said to be the cause of bronchial involvement, because nasal symptoms begin earlier than bronchial symptoms in most patients with SBS. In order to determine whether or not the bronchial involvements are the result of nasal disease, we examined the pulmonary function of patients with CS and SBS.We tested the pulmonary function, vital capacity (VC), forced expiratory volume in 1 sec (FEV10), and corrected values of maximum flows on the flow volume curve at 50% and 25% of the vital capacity (%V50, %V25) of 66 patients with CS without bronchial involvement, or 21 patients with SBS. We also evaluated the pulmonary function of 65 volunteers as a control group. None of them had a history of smoking.VC and FEV1.0 were not decreased in patients with CS. The %V50 and %V25 of those with CS were significantly lower than in the control group (p<0.01) and significantly lower in those with SBS than in those with CS (p<0.01).No positive correlation was found between the duration and severity of CS and the decrease in the level of %V50 and %V25. Some patients had occult peripheral airway dysfunction in the early stage of CS. These findings suggest that CS is not the cause of bronchial involvement and that CS and peripheral airway disorder develop at the same time in some patients, who may later develop SBS.

Pulmonary Function in Patients with Chronic Sinusitis.

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