Clinical course and postmortem findings of a patient with nasopharyngeal carcinoma who died of suppurative meningitis.
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概要
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A 57-year-old patient with nasopharyngeal carcinoma was treated with interferons, anti-cancer drugs and irradiation.He developed suppurative meningitis three years after the diagnosis and died from acute respiratory insufficiency. At autopsy edema of the left cerebral hemisphere was marked and uncal and cingular herniation were noted.Undifferentiated cancer cells were found in the left posterior wall of the sphenoid and left pyramidal bones, but there was no infiltration of cancer cells to the optic nerves or pituitary. The route of both bacterial infection infiltration of cancerous cells was considered to be via the foramen lacerum.
- 耳鼻咽喉科臨床学会の論文