書字検査におけるmacrographismの研究--特に中枢性眩暈症例並びに健常飲酒者群成績よりの検討
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概要
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Macrographism is one of the abnormal findings manifested in the Square Drawing Test (SDT), and its clinical significance has not yet been investigated efficiently. The purposes of this study are to establish its statistical definition, to clarify its clinical significance and also to speculate on the mechanism of macrographism. For the first step, normographism is defined by means of statistical analysis of SDT data obtained from 130 healthy adult subjects. Macrographism is practically defined as having an increase of 20% or more of the length of every line of number 4 square than that of normographism. Fifty-two macrographic cases with vertigo were selected from 975 patients who were examined otoneurologically from January 1979 to December 1981 at Yamaguchi University Hospital. These 52 macrographic cases could be divided into 3 groups: 37 with vertigo of central origin, 7 of otogenic vertigo and the remaining 8 patients of non-central, non-otogenic vertigo.The clinical significance of macrographism is then investigated using the otoneurological data from 37 patients with vertigo of central origin. These vertigo patients are suspected to have diffuse lesions in the brainstem and cerebellum judging from the presence of perverted nystagmus, saccadic eye movement and suppressed optokinetic nystagmus. Sixteen patients with vertigo of central origin had directional preponderance in examinations for spontaneous and provoked nystagmus and they were suspected to have a unilateral lesion in the posterior fossa or cerebral lesion.The alcohol drinking test was then performed. Seventeen healthy adult subjects showed macrographism, in which the variation of data paralleled the alcohol concentration in the breath. The cerebral lesion could be regarded as one of the causes of macrographism judging from the presence of directional preponderance and the pharmacological effect of alcohol in the central nervous system.
- 耳鼻咽喉科臨床学会の論文
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